Preclinical Drug
Development Solutions
Preclinical CRO Support for Drug Development
We provide integrated preclinical CRO support for pharmaceutical and biotech programmes, covering translational research through to IND-enabling studies. Our capabilities include disease models, pharmacology and efficacy evaluation, PK/PD studies, and comprehensive assessment through imaging, pathology and long-term follow-up, across both small- and large-animal platforms. All studies are conducted under GLP-compliant conditions, supporting global development programmes.
Preclinical Drug Development Solutions
Pharmacodynamic Evaluation
Large Animal Models
Myocardial infarction (pig), diabetes (NHP), stroke (dog), and other clinically relevant disease models.
Small Animal Models
Xenograft tumour models, Alzheimer’s disease (transgenic mice), and inflammation models.
GLP Safety Assessment
Acute and chronic toxicity
Genotoxicity and carcinogenicity
Cardiovascular (hERG) and respiratory safety
Biomarker-based risk assessment
Pharmacokinetics & Toxicology (DMPK)
In Vitro Studies
Caco-2 permeability, CYP induction/inhibition, and metabolite profiling.
In Vivo ADME
PK/PD studies in rodents, rabbits, and non-human primates.
Toxicokinetics
Dose range finding and safety margin evaluation.
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Building 11-12, Block B, Lian Dong U Valley, No.29, Bishan Street, Huangpu District, Guangzhou China
Room 503, 5/F Hang Seng Castle Peak Road Building 339 Castle Peak Road Cheung Sha Wan Hong Kong
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